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Initial sequencing and analysis of the human genome.

The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.

Pubmed ID: 11237011

Authors

  • Lander ES
  • Linton LM
  • Birren B
  • Nusbaum C
  • Zody MC
  • Baldwin J
  • Devon K
  • Dewar K
  • Doyle M
  • FitzHugh W
  • Funke R
  • Gage D
  • Harris K
  • Heaford A
  • Howland J
  • Kann L
  • Lehoczky J
  • LeVine R
  • McEwan P
  • McKernan K
  • Meldrim J
  • Mesirov JP
  • Miranda C
  • Morris W
  • Naylor J
  • Raymond C
  • Rosetti M
  • Santos R
  • Sheridan A
  • Sougnez C
  • Stange-Thomann N
  • Stojanovic N
  • Subramanian A
  • Wyman D
  • Rogers J
  • Sulston J
  • Ainscough R
  • Beck S
  • Bentley D
  • Burton J
  • Clee C
  • Carter N
  • Coulson A
  • Deadman R
  • Deloukas P
  • Dunham A
  • Dunham I
  • Durbin R
  • French L
  • Grafham D
  • Gregory S
  • Hubbard T
  • Humphray S
  • Hunt A
  • Jones M
  • Lloyd C
  • McMurray A
  • Matthews L
  • Mercer S
  • Milne S
  • Mullikin JC
  • Mungall A
  • Plumb R
  • Ross M
  • Shownkeen R
  • Sims S
  • Waterston RH
  • Wilson RK
  • Hillier LW
  • McPherson JD
  • Marra MA
  • Mardis ER
  • Fulton LA
  • Chinwalla AT
  • Pepin KH
  • Gish WR
  • Chissoe SL
  • Wendl MC
  • Delehaunty KD
  • Miner TL
  • Delehaunty A
  • Kramer JB
  • Cook LL
  • Fulton RS
  • Johnson DL
  • Minx PJ
  • Clifton SW
  • Hawkins T
  • Branscomb E
  • Predki P
  • Richardson P
  • Wenning S
  • Slezak T
  • Doggett N
  • Cheng JF
  • Olsen A
  • Lucas S
  • Elkin C
  • Uberbacher E
  • Frazier M
  • Gibbs RA
  • Muzny DM
  • Scherer SE
  • Bouck JB
  • Sodergren EJ
  • Worley KC
  • Rives CM
  • Gorrell JH
  • Metzker ML
  • Naylor SL
  • Kucherlapati RS
  • Nelson DL
  • Weinstock GM
  • Sakaki Y
  • Fujiyama A
  • Hattori M
  • Yada T
  • Toyoda A
  • Itoh T
  • Kawagoe C
  • Watanabe H
  • Totoki Y
  • Taylor T
  • Weissenbach J
  • Heilig R
  • Saurin W
  • Artiguenave F
  • Brottier P
  • Bruls T
  • Pelletier E
  • Robert C
  • Wincker P
  • Smith DR
  • Doucette-Stamm L
  • Rubenfield M
  • Weinstock K
  • Lee HM
  • Dubois J
  • Rosenthal A
  • Platzer M
  • Nyakatura G
  • Taudien S
  • Rump A
  • Yang H
  • Yu J
  • Wang J
  • Huang G
  • Gu J
  • Hood L
  • Rowen L
  • Madan A
  • Qin S
  • Davis RW
  • Federspiel NA
  • Abola AP
  • Proctor MJ
  • Myers RM
  • Schmutz J
  • Dickson M
  • Grimwood J
  • Cox DR
  • Olson MV
  • Kaul R
  • Raymond C
  • Shimizu N
  • Kawasaki K
  • Minoshima S
  • Evans GA
  • Athanasiou M
  • Schultz R
  • Roe BA
  • Chen F
  • Pan H
  • Ramser J
  • Lehrach H
  • Reinhardt R
  • McCombie WR
  • de la Bastide M
  • Dedhia N
  • Blöcker H
  • Hornischer K
  • Nordsiek G
  • Agarwala R
  • Aravind L
  • Bailey JA
  • Bateman A
  • Batzoglou S
  • Birney E
  • Bork P
  • Brown DG
  • Burge CB
  • Cerutti L
  • Chen HC
  • Church D
  • Clamp M
  • Copley RR
  • Doerks T
  • Eddy SR
  • Eichler EE
  • Furey TS
  • Galagan J
  • Gilbert JG
  • Harmon C
  • Hayashizaki Y
  • Haussler D
  • Hermjakob H
  • Hokamp K
  • Jang W
  • Johnson LS
  • Jones TA
  • Kasif S
  • Kaspryzk A
  • Kennedy S
  • Kent WJ
  • Kitts P
  • Koonin EV
  • Korf I
  • Kulp D
  • Lancet D
  • Lowe TM
  • McLysaght A
  • Mikkelsen T
  • Moran JV
  • Mulder N
  • Pollara VJ
  • Ponting CP
  • Schuler G
  • Schultz J
  • Slater G
  • Smit AF
  • Stupka E
  • Szustakowski J
  • Thierry-Mieg D
  • Thierry-Mieg J
  • Wagner L
  • Wallis J
  • Wheeler R
  • Williams A
  • Wolf YI
  • Wolfe KH
  • Yang SP
  • Yeh RF
  • Collins F
  • Guyer MS
  • Peterson J
  • Felsenfeld A
  • Wetterstrand KA
  • Patrinos A
  • Morgan MJ
  • de Jong P
  • Catanese JJ
  • Osoegawa K
  • Shizuya H
  • Choi S
  • Chen YJ
  • Szustakowki J
  • International Human Genome Sequencing Consortium

Journal

Nature

Publication Data

February 15, 2001

Associated Grants

  • Agency: NHGRI NIH HHS, Id: U54 HG003273

Mesh Terms

  • Animals
  • Chromosome Mapping
  • Conserved Sequence
  • CpG Islands
  • DNA Transposable Elements
  • Databases, Factual
  • Drug Industry
  • Evolution, Molecular
  • Forecasting
  • GC Rich Sequence
  • Gene Duplication
  • Genes
  • Genetic Diseases, Inborn
  • Genetics, Medical
  • Genome, Human
  • Human Genome Project
  • Humans
  • Mutation
  • Private Sector
  • Proteins
  • Proteome
  • Public Sector
  • RNA
  • Repetitive Sequences, Nucleic Acid
  • Sequence Analysis, DNA
  • Species Specificity