Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization.

Journal:

FASEB J. 2001 May

Authors:

Koushik SV, Wang J, Rogers R, Moskophidis D, Lambert NA, Creazzo TL, Conway SJ

Abstract

PMID: 11344090

Mesh Headings:

Animals, Calcium, Embryonic and Fetal Development, Gene Targeting, Genes, Reporter, Heart, Immunohistochemistry, Mice, Mice, Transgenic, Morphogenesis, Myocardial Contraction, Myocardium, Sodium-Calcium Exchanger