High frequency of mutations of the PIK3CA gene in human cancers.

Journal:

Science 2004 Apr

Authors:

Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, Szabo S, Yan H, Gazdar A, Powell SM, Riggins GJ, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VE

Abstract

Mesh Headings:

Breast Neoplasms, Catalytic Domain, Colorectal Neoplasms, Glioblastoma, Humans, Lung Neoplasms, Mutation, Neoplasms, Phosphatidylinositol 3-Kinases, Sequence Analysis, DNA, Stomach Neoplasms