GOChase: correcting errors from Gene Ontology-based annotations for gene products.

Journal:

Bioinformatics 2005 Mar

Authors:

Park YR, Park CH, Kim JH

Abstract

SUMMARY: The Gene Ontology (GO) is a controlled biological vocabulary that provides three structured networks of terms to describe biological processes, cellular components and molecular functions. Many databases of gene products are annotated using the GO vocabularies. We found that some GO-updating operations are not easily traceable by the current biological databases and GO browsers. Consequently, numerous annotation errors arise and are propagated throughout biological databases and GO-base
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d high-level analyses. GOChase is a set of web-based utilities to detect and correct the errors in GO-based annotations.[less]

Mesh Headings:

Database Management Systems, Databases, Protein, Documentation, Information Storage and Retrieval, Natural Language Processing, Proteins, Quality Control, Software, User-Computer Interface, Vocabulary, Controlled, Word Processing