The LIFEdb database in 2006.

Journal:

Nucleic Acids Res. 2006 Jan

Authors:

Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S

Abstract

LIFEdb (http://www.LIFEdb.de) integrates data from large-scale functional genomics assays and manual cDNA annotation with bioinformatics gene expression and protein analysis. New features of LIFEdb include (i) an updated user interface with enhanced query capabilities, (ii) a configurable output table and the option to download search results in XML, (iii) the integration of data from cell-based screening assays addressing the influence of protein-overexpression on cell proliferation and (iv) th

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e display of the relative expression ('Electronic Northern') of the genes under investigation using curated gene expression ontology information. LIFEdb enables researchers to systematically select and characterize genes and proteins of interest, and presents data and information via its user-friendly web-based interface.[less]

PMID: 16381901

Mesh Headings:

Cell Proliferation, Computational Biology, DNA, Complementary, Databases, Genetic, Gene Expression, Genes, Genomics, Internet, Proteins, Recombinant Fusion Proteins, Systems Integration, User-Computer Interface