The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping.

Journal:

Mamm. Genome 2012 Oct

Authors:

Brown SD, Moore MW

Abstract

Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse pr
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oduction and phenotyping.[less]

Mesh Headings:

Animals, Internationality, Mice, Mice, Mutant Strains, Phenotype