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CATIE - Clinical Antipsychotic Trials in Intervention Effectiveness

The NIMH-funded Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Study was a nationwide public health-focused clinical trial that compared the effectiveness of older (first available in the 1950s) and newer (available since the 1990s) antipsychotic medications used to treat schizophrenia. These newer medications, known as atypical antipsychotics, cost roughly 10 times as much as the older medications. CATIE is the largest, longest, and most comprehensive independent trial ever done to examine existing therapies for this disease. Schizophrenia is a brain disorder characterized by hallucinations, delusions, and disordered thinking. The course of schizophrenia is variable, but usually is recurrent and chronic, often causing severe disability. Previous studies have shown that taking antipsychotic medications consistently is far more effective than taking no medicine and that the drugs are necessary to manage the disease. The aim of the CATIE study was to determine which medications provide the best treatment for schizophrenia. Additional information may be found by following the links, http://www.nimh.nih.gov/trials/practical/catie/index.shtml, http://www.clinicaltrials.gov/ct/show/NCT00014001?order=1

URL: http://www.nimh.nih.gov/health/trials/practical/catie/index.shtml

Resource ID: nlx_146233     Resource Type: Resource     Version: Latest Version

Keywords

schizophrenia, clinical trial, treatment, outcome, antipsychotic

Additional Resource Types

clinical trial

Alternate URLs

http://www.nimh.nih.gov/health/trials/practical/catie/phase1results.shtml

Related Disease

Schizophrenia

Supercategory

Resource

Abbreviation

CATIE, CATIE Schizophrenia

Synonyms

Clinical Antipsychotic Trials in Intervention Effectiveness, CATIE Schizophrenia Study, Clinical Antipsychotic Trials in Intervention Effectiveness - Schizophrenia

Parent Organization

Resource Status

Last checked down;

Curation Status

curated

Listed By

ClinicalTrials.gov

Old URLs

http://www.catie.unc.edu/schizophrenia/index.html

Species

human

Original Submitter

Anonymous

Version Status

Curated

Submitted On

12:00am June 14, 2012

Originated From

SciCrunch

Changes from Previous Version

First Version

Version 1

Created 3 years ago by Anonymous