Dendritica is a program package for relating dendritic geometry and signal propagation. The programs are based on those used for the simulations described in the following paper: Vetter, P., Roth, A. & Husser, M. (2001). Action potential propagation in dendrites depends on dendritic morphology. Journal of Neurophysiology, 85: 926-937.
Dendritica can functionally be divided into three main parts:
- Interactive morphological analysis and electrophysiological simulation of single cells
- Automated batch simulations across a set of morphologies using the same simulation parameters
- Automated analysis of batch simulation runs
Dendritica requires NEURON 4.1.1 with some modifications described in Appendix 1. It was tested for NEURON 4.1.1 on Linux and SGI IRIX. Some modifications to the Dendritica code may be necessary in order to run it on older or newer versions of NEURON.
Sponsors: This work was supported by the Wellcome Trust, the European Community, the Max-Planck-Gesellschaft, the Wellcome Trust 4-year PhD Programme in Neuroscience.
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electrophysiological simulation, dendritic geometry, interactive, morphological, morphology, neuron, sigle cell, signal propagation
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software resource, simulation software
Created 4 years ago by Anonymous