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Tumorbank Basel Foundation

Since 1995 the Tumorbank Basel Foundation (German: Stiftung Tumorbank Basel) is a non-for-profit foundation acting in cancer translation research. The purpose of the Tumorbank Basel Foundation is to support in promoting optimization of decision making process for the management of solid cancer personalized treatment modalities to the benefit of the patient. Our Aims: * Acquisition and storage of biological material and clinical data of patients suffering of solid cancer diseases in particular breast and prostate cancer. * Promoting and supporting cancer research using the acquired material and data for clinical studies and translational research. * The development of molecular tumor analyses / tools for cancer patients and the performance of the resulting diagnostic services for personalized treatment modalities. The Tumorbank Basel Foundation has acquired * Data about more than 10'000 breast cancer patients * Data comprise clinical and pathological (histology & IHC) characteristics and biochemical (continuous quantified protein expression levels) features, which are available for almost all samples as well as clinical follow-ups now available for more than 2'000 patients * The RNA expression level of 65 genes has been assessed in >800 samples by Real-Time PCR (317 retrospectively in cases with follow-up, the remaining on a routine basis, prospectively since 2004) The Tumorbank Basel Foundation is storing in Freezers at - 80 degrees C * Ca. 6'000 fresh frozen tissue samples of breast cancer patients * Ca. 9'000 particulate fractions (cytosol / membrane) of all samples analyzed * Ca. 1'000 paired non-malignant adjacent tissue material samples * More than 1'000 extracted RNA samples of good quality * Serum and plasma collection from patients has been started since 2005 All data are stored in a relational SQL data bank using an application. The Tumorbank Basel Foundation is collaborating with several pathology institutes allowing to perform studies correlating results obtained from fresh frozen and paired paraffin embedded tissue samples. The Tumorbank Basel Foundation has started a prostate carcinoma project in Collaboration with the ZeTuP (www.zetup.ch) and pathology institute of St. Gallen. Fresh frozen samples of more than 150 prostate carcinoma patients have been collected and are under investigation.

URL: http://www.tumorbank.org/index.php

Resource ID: nlx_143986     Resource Type: Resource     Version: Latest Version

Keywords

tissue, tumor tissue, serum, plasma, rna, particulate fraction, clinical data, frozen, fresh frozen, paraffin embedded, cancer, breast cancer, prostate cancer, solid cancer disease

Curation Status

curated

Related Application

Research

Supercategory

Resource

Abbreviation

Tumorbank Basel Foundation

Additional Resource Types

tissue bank, database, biomaterial supply resource, material storage repository

Related Disease

Cancer, Breast cancer, Prostate cancer, Solid cancer disease

Resource Status

Last checked down;

Synonyms

Stiftung Tumorbank Basel

Listed By

One Mind Biospecimen Bank Listing, European Biobank

Processing

Frozen, Fresh frozen, Paraffin embedded

Comment

Sample type: Tissue, Tumor tissue, Serum, Plasma, RNA, Particulate fraction

Availability

Collaborators: The Tumorbank Basel Foundation is collaborating with several pathology institutes allowing to perform studies correlating results obtained from fresh frozen and paired paraffin embedded tissue samples.

Species

human

Original Submitter

Anonymous

Version Status

Curated

Submitted On

12:00am January 23, 2012

Originated From

SciCrunch

Changes from Previous Version

First Version

Version 1

Created 3 years ago by Anonymous