Cell Line Confirmation - What is this?

• Cell line Confirmation: expected when a cell line is detected

  • Cell Line Authentication

    • MDAR, NIH

    • A statement detailing how the cell lines used were authenticated (e.g. short tandem repeat analysis). This is only required when cell lines are detected.

    • If we find a statement about cell line authentication, then SciScore expects to find the following items (sex, randomization, blinding, power);

    • Example: MOLM-14 cells were authenticated by STR profiling and flow cytometry.

  • Cell Line Contamination Check

    • MDAR, NIH

    • A statement addressing the mycoplasma contamination status of the cell lines used. This is only required when cell lines are detected.

    • If we find a statement about contamination of cell lines, then SciScore expects to find the following items (sex, randomization, blinding, power);

    • Example: All cell lines were obtained from ATCC and tested negative for mycoplasma contamination.